Place the XLR8 over the area of involvement (AOI). The clinician may choose to (#2) laser over the nerve root (located using the myotome/dermatome chart) or the organ involved (using the Merrick chart).
With systemic infections laser the radial pulse or carotid artery or femoral artery. This is where the absolute most blood flow is in the body, and it is the most superficial. Also laser over the large intestine and the entire spine.